The hydroxychloroquine flap

It is so frustrating to see the Democrats in media still hoping this drug will fail.  PSA: Not all drugs work for all people. THC helps some and not others. Aspirin is a miracle drug for many but doesn't help everyone. Many cannot use Tylenol. Ever talk to someone trying to get just the right Parkinson's treatment--one size/treatment doesn't work. And statins? Oh my--cripples some with mysterious muscle problems and cures others. I use fish oil for bursitis, and even if it is a placebo, it works for me--maybe not for you. Peer review articles by researchers don't always agree. Politics seems to be the best disinfectant going these days--wiping the brain cells of Trump haters clean

Dr. Anna Meenan says they can get away with it for now, because it has a strange name that no one except the doctors and the president can pronounce, and it's normally used for unusual indications (malaria prevention, lupus). It is no more dangerous than penicillin (allergic reactions and rashes in some people) in short term use. If someone discovered that penicillin seemed to work on this virus, you can bet they would be clamoring for it. The data is looking better and better for hydroxychloroquine when used early in the course of the illness. I predict those MSM pundits will have to eat their words eventually. It's not a cure-all, but it will have a place in treatment.

Diane McDermott says India had banned the export of this drug. Trump called them and told them to end the ban, that we want that drug and that we need it. India 2 days later ends the export ban and supplies us with the drug.

Our dependence on China for prescription drugs

https://sharylattkisson.com/2020/02/china-syndrome-our-surprising-dependence-on-china-for-our-prescription-drugs/

This was from 2018 by Sharyl Attkisson—but even more alarming today with the coronavirus.

Sharyl Attkisson: In the 1990’s, the US, Europe, and Japan manufactured 90 percent of the key ingredients from medicine and vitamins. But now China is the largest global supplier. Why the change?

Rosemary Gibson: The change is because when we started buying generic drugs, which are terrific because they can be a lot less costly than brand name drugs, we had to find a cheaper way to make them. And China was more than willing with its lower labor costs to be a place where companies could buy those key ingredients.

Sharyl Attkisson: We’re talking about antibiotics, chemotherapies antidepressants. What other kinds of things?

Rosemary Gibson: Well, now, the generic drugs that we’re buying from China and Chinese companies in China include blood pressure medicines, Alzheimer’s, Parkinson’s, epilepsy, antidepressants the whole range of generic drugs now that we are importing from China.

And more. . .

Patch, pill or hypnosis, how did you quit?

I'm still waiting to meet a former smoker who quit permanently as the result of a government paid for program in their health plan, a work sponsored program, a drug patch or pill, hypnosis, talk therapy, etc. And I don't mean the 3-6 month quitter that the research reports in a clinical study so they get another grant from the NIH.  I'm sure they are out there, or why would we be spending so much money on them? [sarcasm].

Just Google "Smoking Cessation programs" (about 4.5 million hits).  Mayo Clinic claims it's had 45,000 participants in its program to stop using tobacco (smoking and chewing), with 110 randomized clinical trials involving more than 25,000 research subjects.  Where are the success stories?

When I see reports on what percentage of income the poor spend on cigarettes, there is usually a follow up appeal on why we should be spending more money on helping them quit.  Put where is the research that pills, patches, hypnosis and counseling actually pay?

http://www.nytimes.com/2012/09/20/nyregion/poor-smokers-in-new-york-state-spend-25-of-income-on-cigarettes-study-says.html?_r=0

Current Drug Shortages--Some hospitals are in tough shape

What's behind this? Seems to be a much bigger problem than 2007 and 2008. Is it the impending doom of Obamacare? Years of over regulation? Loss of profit by the manufacturers, who afterall, aren't in this as volunteers or church ladies.

"The supply of these drugs has tightened in recent years as the generic-drug industry has consolidated, with many of the drugs now made by just one or two companies. In many cases patents have long expired and the original brand-name drug is no longer being produced.

Federal regulators have also stepped up enforcement of quality standards, limiting the ability of large manufacturers to ramp up production.

The drugs—typically used in hospitals and outpatient clinics—often require complex manufacturing processes with long lead times. Because factories produce many kinds of medicines, companies say they can't easily make more of one without creating a shortage in another.

The Food and Drug Administration reported a record 178 drug shortages in 2010, up from 157 the year earlier and 55 five years ago"

Drug Shortages Distress Hospitals - WSJ.com

The Reality of Drug Shortages — The Case of the Injectable Agent Propofol | Health Policy and Reform

Read list of Drug Shortages > Current Drug Shortages

3611

I shouldn't be surprised, but I was

Medical staff need special training to learn to use alcohol hand disinfectants properly. Who knew?

There was an alarming story in the WSJ this morning about antibiotic resistant super bugs (Henry Masur, President of Infectious Diseases Society of America). He said that annually nearly 2 million U.S. patients acquire infections in the hospital and nearly 1 in 10 die, and more than 70% of those infections are resistant to at least one of the drugs used to treat them. We have so over regulated big pharm and the market is so limited, that research on new antibiotics is stalled. In the past 15 years FDA has approved approximately the same number of new antiviral medications that target HIV as it has antibiotics to treat all bacterial infections combined. Yet, thousands and thousands die of resistant strains of bacteria. It's market forces and length of time to get approved. Many, many people with HIV, but limited number in the groups affected by all the different bacteria. Also, there is no political lobby or Hollywood movie stars putting on benefits for the rest of us who develop a raging infection in the hospital.

We're losing more people to this than to HIV. What good will it do the gay guy if you save him from his past only to have him die of a bug that's resistant to antibiotics?

Anyway, back to the hand rubs. I searched Medline for "antibiotics AND resistance" and got something like 35,000 hits, so I reentered the search adding hospitals, and eventually I found this little gem: "Introducing alcohol-based hand rub for hand hygiene: the critical need for training." Infect Control Hosp Epidemiol. 2007; 28(1):50-4.

RESULTS: At baseline, only 31% of Health Care Workers (HCW) used proper technique, yielding a low reducation factor (RF) of 1.4 log(10) colony-forming units (cfu) bacterial count. Training improved HCW compliance to 74% and increased the RF to 2.2 log(10) cfu bacterial count, an increase of almost 50% (P<.001). Several factors, such as applying the proper amount of hand rub, were significantly associated with the increased RF. CONCLUSION: These results demonstrate that education on the proper technique for using hand rub, as outlined in European Norm 1500 (EN 1500), can significantly increase the degree of bacterial killing.

Well, what do you know! Makes me think of kindergarten when we were taught how to wash our hands. Is that still taught in public schools?

Bad bugs need drugs campaign