Two years ago, end of radiation

Two years ago Bob ended his radiation for prostate cancer and Phil was with him to ring the bell.

Prostate cancer and nutrition

An excellent summary (2009) of recent research on nutrition, diet, exercise and genetics of prostate cancer.

That's a lot of veggies!

The following is from the Harvard Medical School HealthBeat, May 28, 2015

"Several studies have shown that in countries where men eat a typical "Western" diet containing a large amount of meat, the incidence of prostate cancer, especially aggressive prostate cancer, is higher than in countries where plant-based foods are a primary part of the diet. Unfortunately, these studies weren't designed to prove cause and effect. So for now, definitive answers about prostate cancer and diet aren't yet in — although researchers are actively studying this topic.

Investigators have launched a federally funded national study to see whether a diet that's higher in plant-based foods and lower in animal-based foods than the typical Western diet will help control tumor growth in men with early-stage prostate cancer.

Participants in the Men's Eating and Living (MEAL) study will try to eat nine servings of fruits and vegetables daily — significantly more than the three to four servings consumed each day by the typical American man — as well as two servings of whole grains and one serving of beans or other legumes.

This clinical trial will include men 50-80 years old who have small, low-grade tumors and who have opted to have their condition followed closely (active surveillance) rather than undergoing immediate treatment. Researchers will randomly assign participants to telephone counseling about how to achieve the dietary MEAL goals or to a control group that receives standard dietary advice for Americans.

During the two-year study, the investigators will collect blood samples to assess levels of antioxidants and nutrients, and then monitor the men with PSA tests and prostate biopsies to determine whether the cancer is progressing. A pilot study showed the approach is workable, and that with enough telephone prompting, men can increase their intake of vegetables and other healthy foods. To learn more about the larger phase III MEAL study, or to enroll, visit www.clinicaltrials.gov and search for Trial NCT 01238172."

Blood vessels might predict prostate cancer

"The study of 572 men with localized prostate cancer indicates that aggressive or lethal prostate cancers tend to have blood vessels that are small, irregular and primitive in cross-section, while slow-growing or indolent tumors have blood vessels that look more normal.

The findings were published Oct. 26 in the Journal of Clinical Oncology. OSU news release. . .

"It's as if aggressive prostate cancers are growing faster and their blood vessels never fully mature," says study leader Dr. Steven Clinton, professor of medicine and a medical oncologist and prostate cancer specialist at Ohio State's Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute.

"Prostate cancer is very heterogeneous, and we need better tools to predict whether a patient has a prostate cancer that is aggressive, fairly average or indolent in its behavior so that we can better define a course of therapy surgery, chemotherapy, radiotherapy, hormonal treatment, or potentially new drugs that target blood vessels that is specific for each person's type of cancer," Clinton says.

Isn't that just so silly? Everyone knows who's been following JAMA for years that nothing happens in medicine that isn't about poverty, race, education or poor nutrition. If it were, there might be more grant money released for true research instead of keeping all those social science folk employed writing papers and applying for more grants.