Showing posts with label biomedical research. Show all posts
Showing posts with label biomedical research. Show all posts

Friday, January 22, 2021

Subscriptions (digital) to keep me up to date

I subscribe to several medical information services because for years I was a veterinary medicine librarian and sort of got hooked on the genre. (I was also a librarian for Russian and Soviet studies, Latin American studies, and Agriculture in earlier jobs.) However, I've seen quite a change in the last 20 years. I also get the printed version of JAMA. It's really disappointing to see science going the way of intersectionality.

I subscribe to research from START (The National Consortium for the Study of Terrorism and Responses to Terrorism) which "prides itself on the diversity of research conducted across the Consortium to bring a holistic understanding to the study of terrorism, counterterrorism and community resilience. START researchers based throughout the United States and around the world bring varying perspectives, experiences, and academic disciplines to their analysis." It doesn't live up to its advertising of mission statement.

I subscribe to beSpacific "Accurate, Focused Research on Law, Technology and Knowledge Discovery Since 2002" And so liberal I sometimes scream at the screen when I see what she's covering. Librarianship, gotta love it. It's mostly political bias, but at least you know what you're up against.

Thursday, April 16, 2020

A call for plasma

Today I read "that Ohio State researchers and clinicians have found a way to take plasma from someone who has recovered from COVID-19 and deliver it to patients who are currently battling the virus to aid in their treatment and recovery." Hey, that's great news. But in that e-mail people who'd had Covid19 and been symptom free for 28 days were urged to donate plasma. Huh? Don't we have a billion dollars worth of EMR in Ohio and the other 49 plus DC and territories so some researcher can data mine our health records even if our MD has to call for it? Doesn't Dr. Brix always say, "the data show?" If the first known death was Feb. 29 in the U.S. and it wasn't in Ohio and many had it and didn't know it, maybe even me or you, should everyone who's had a mysterious cold or cough since the fall be tested?

Ohio has had less than 8,000 confirmed cases and barely over 2,000 were hospitalized. Doctors' offices are swamped with calls from clients who can't even be tested without all the signs. Surely somewhere in all those computers there's a record of the people to contact.

And President Trump will probably be blamed for OSU not knowing where to look for donated plasma. After all, isn't it his fault he didn't close down the economy before anyone had died?

Sunday, April 12, 2020

Sowing fear and distrust about hydroxychloroquine

While the media, including NPR, try to frighten people about "unproven" emergency use of Hydroxychloroquine and chloroquine here's what CDC says about therapeutic options:

https://www.cdc.gov/coronavirus/2019-ncov/hcp/therapeutic-options.html? which links to the authorization of its use while clinical trials are performed. It won't harm anyone, and could help many based on trials in other countries. The media hate Trump so much they will try anything:

"On February 4, 2020, pursuant to Section 564(b)(1)(C) of the Act, the Secretary of the Department of Health and Human Services (HHS) determined that there is a public health emergency that has a significant potential to affect national security or the health and security of United States citizens living abroad, and that involves the virus that causes COVID-19.3 ,4 Pursuant to Section 564 of the Act, and on the basis of such determination, the Secretary of HHS . . . Based upon limited in-vitro and anecdotal clinical data in case series, chloroquine phosphate and hydroxychloroquine sulfate are currently recommended for treatment of hospitalized COVID-19 patients in several countries, and a number of national guidelines report incorporating recommendations regarding use of chloroquine phosphate or hydroxychloroquine sulfate in the setting of COVID-19. FDA encourages the conduct and participation in randomized controlled clinical trials that may produce evidence concerning the effectiveness of these products in treating COVID-19. FDA is issuing this EUA to facilitate the availability of chloroquine phosphate and hydroxychloroquine sulfate during the COVID-19 pandemic to treat patients for whom a clinical trial is not available, or participation is not feasible. "

Also notice the date. Feb. 4. While Democrats and their media arms were calling Trump a racist for attempting to limit entry to our country by infected people.

Tuesday, November 12, 2019

Google and our health data

According to a story I watched on Fox today, we're not to be concerned that Google is controlling and distributing our health information and data--they are being HIPAA compliant. Big Whoop. What about being compliant with our wishes, with our concerns? Remember Henrietta Lacks? Did her medical information only matter because she was black? Researchers are lusting for this information--imagine having the data for 1500-2000 people with disease xyz with a key stroke instead of the 30 or 40 you can find with months of appeals and research. And cha ching, your data is part of a study which may bring the researcher/company millions.

https://www.engadget.com/2019/11/11/google-ascension-patient-records-project-nightingale/

https://www.hopkinsmedicine.org/henriettalacks/

Friday, March 27, 2015

Gray Matters, vol. 2

It’s difficult for me to put the word ethics and President Obama in the same sentence—he lied about his support for gay marriage in 2008 in order to get elected and then lied again  in 2012 and said his view “evolved;” he lied about Obamacare in order to get support from Catholic politicians;  he lied about insured Americans being able to keep their plan or doctor when he knew it wasn’t true; he believes  abortion is a woman’s health issue and gives our tax money to Planned Parenthood, allowing killing the unborn for any reason, even gender and disability, at any point in the pregnancy; he’s inserted himself into “race conversations” when he didn’t have the facts, like the Boston police incident with Professor Gates and the Trayvon Martin case in Florida; he pulled out the troops prematurely from Iraq ignoring his military advisors allowing ISIS to swarm so he could meet a campaign promise, and then claimed victory; he touts Bowe Bergdahl’s release in the Rose Garden while calling Ft. Hood workplace violence denying the injured special medical benefits; and on and on.  No, ethical is not a word that comes to mind.

But here is it: “Commission Releases Gray Matters, Vol. 2 – final response to President Obama’s BRAIN Initiative related request Commission focuses on three controversial issues that must be addressed if neuroscience is to progress and be applied ethically”

 See more at: http://bioethics.gov/node/4715#sthash.Q6kR6TQ2.dpuf

Thursday, December 15, 2011

A face only a mother could love

Alert PETA. Trouble ahead. The naked mole rat is a useful model for aging and cancer. "The strictly subterranean naked mole rat lives as long as 30 years and shows negligible senescence, no age-related increase in mortality, high fertility until death, and resistance to spontaneous cancer and experimentally induced tumorigenesis. They also live in full darkness at low oxygen and high carbon dioxide concentrations and are unable to sustain thermogenesis or feel certain types of pain. " Nature, via JAMA, Dec. 7, 2011

Tuesday, July 06, 2010

Bio-medical research

Remember how Obama was applauded for his promises to pour more money into biomedical research? Well, it happened--sort of. JAMA reports when the 2011 budget is adjusted for inflation, there is no increase, and there is actually LESS because the ARRA stimulus infusion of $10.4 billion comes to an end.

In the coffee shop I saw a woman with a 30 year old face and the body of a 12 year old. Maybe she has EDNOS? That means she hasn't been diagnosed with anorexia (self starvation) or bulimia (binging and purging), but an "eating disorder not otherwise specified." EDNOS actually has a higher mortality than anorexia or bulimia, but seems to be in a limbo of medical indecision on how to classify it.

In another issue of JAMA I saw an article about race and aggressive treatment at the end of life and survival in long term acute care facilities. It seems that black patients at the end of life prefer a more aggressive treatment. They are less likely to have do-not-resuscitate orders in place at the time of hospitalization and are less likely to favor withdrawal of life sustaining measures in the ICU. Such a dilemma for a progressive, liberal publication. Is this liberal or conservative? Cultural? Religious? Racial? Moral?

The end result is African-American patients are sicker when they transfer to a long term facility and are less likely to survive--the whites who were the sickest with the poorest prognosis died in the acute care hospital! So blacks are more likely to die while ventilator dependent. But then the writers (social workers and PhD types) have to face the fact that this unplanned, unforeseen racial/cultural disparity opens up financial incentives for physician owned specialty hospitals, and home health services. Capitalism! Oh the horror! Better the government panel step in and decide their fate, right?

Friday, August 21, 2009

Or he could have asked me a vet med librarian

I had noticed this back in the 1990s when I was writing my own articles and/or helping professors do their research. On-line didn’t mean better research, and sometimes it didn’t mean faster.
    James Evans writes for Britannica Blog: “For a report published in Science (July 18, 2008), I used a database of 34 million articles, their citations (1945 to 2005) and online availability (1998 to 2005), and showed that as more journals and articles came online, the actual number of them cited in research decreased, and those that were cited tended to be of more recent vintage. This proved true for virtually all fields of science. (Note that this is not a historical trend…there are more authors and universities citing more and older articles every year, but when journals go online, references become more shallow and narrow than they would have been had they not gone online.)

    Moreover, the easy online availability of sources has channeled researcher attention from the periphery to the core—to the most high-status journals. In short, searching online is more efficient, and hyperlinks quickly put researchers in touch with prevailing opinion, but they may also accelerate consensus and narrow the range of findings and ideas grappled with by scholars.”
When professors came to the library, sat down with their favorite, generalist journal on medicine, biochemistry, nutrition, or cancer, they would scan the table of contents, and couldn’t avoid seeing areas of interest outside their own, something to perk a brain cell in a new direction. On-line database searching narrows and refines, but it also imprisons the mind.

Tuesday, February 10, 2009

500 new jobs and $60 million more in salaries and expenditures for central Ohio

If you have a weak spam filter like my osu dot edu mail box, you’re probably getting a lot of mail about “enhancement” and “enlargement.” I suppose this reflects desperate times for gullible Americans, or eager spammers who think every one with a dot edu mailbox must be 19 years old, or maybe just poor IT security at OSU. No matter how many blocks I add to the word list, they just find more creative ways to discuss sex. Once in awhile there is interesting news in the mail box from Chip and Steve, from whom I hear often. Chip Souba, Vice President and Executive Dean for Health Sciences and Steven G. Gabbe, Senior Vice President for Health Sciences, OSU Medical Center. Today I learned:
    "We are pleased to inform you that The Ohio State University Board of Trustees approved funds last Friday to proceed with interior design work for the final three floors of the Biomedical Research Tower (BRT). Floors 4, 5 and 6 were left as unfinished shells until the funding and research priorities for the space were identified.

    This project will add approximately 72,000 usable square feet of research space to our Medical Center, which is absolutely essential to reach our goals of being a top-20 academic medical center and a top-10 cancer program nationally. It will eventually allow us to recruit as many as 42 new researchers and their staffs to Ohio State, which translates into 500 new jobs and $60 million more in salaries and expenditures for our local economy."
Now that’s the kind of expansion we can all appreciate, assuming it was not just part of another phony stimulus. And I can only hope that human embryos aren't part of that planned research--adult stem cell research is leaps and bounds ahead of embryonic, thanks to GWB holding the ethical line.