Humanized mice, Covid and bioethics

When I begin to read a medical article, and a phrase introduces a topic with, "Although Florida Governor Ron DeSantis and Texas Governor Greg Abbott have promoted monoclonal antibodies while opposing vaccine and mask mandates, they're not a substitute for Covid-19 vaccines." 

You have to read it carefully, though. They are not against vaccines or masks, only the mandates. Opposing mandates is a political stance. It's about opposing growing totalitarianism, the huge failures of Biden and the lies of Fauci. This journal obviously is political too--JAMA (Journal of the American Medical Association)

But here's my question for medical/scientific folks, because I'm way over my pay grade here: the monoclonal antibodies for Covid preexposure prophylaxis use 'humanized mice" in their development. Is that for testing or is some of that matter passed into our system? Using animals as chimeras is not new, but the bioethics of this seem to only be discussed in some committee locked in a closet in a research institution. Maybe in Wuhan?

'Humanized mice': Chimeras fuel quest to treat chronic diseases, cancer and even COVID-19 - Genetic Literacy Project

Part mouse, Part human - Science in the News (harvard.edu)

Democrats are at it again

I remember how the media chided President Bush for being a dim bulb, stupid, etc., but don't recall members of Congress going after him--at least not in speeches demanding removal from office. The Obama lapdog media shut up about that when comparing Bush's extensive reading list to Obama's i-pod selection--hip hop, etc. Trump uses Twitter the way FDR used the radio--to reach and encourage his supporters. It keeps him constantly trolling the press and his fans love it. What the media/politicians called outrageous, like the twitter comment about Obama spying on him, have been proven to be true. Democrats are deeply upset that President Trump is rolling back their eight years of "progress" toward complete socialism.  The Russia, Russia, Russia hysteria has failed miserably, so now they are going after crazy and not smart--but that's what they are. His 80+ accomplishments in 2017 are just chimeras in their exploding, failing minds. Like the ad I see on TV about the guy with dementia seeing things that aren't there.