Hope for a terrible disease--Dengue Fever

Mexico has approved the world’s first dengue virus vaccine. Sanofi’s Dengvaxia will be available to children over nine and adults 45 and under. . . Sanofi spent two decades and $1.6 billion on the development of Dengvaxia. According to BBC News, about 40,000 people in Mexico will initially receive the shot. “With this decision, Mexico moves ahead of all other countries, including France, to tackle the spread of this virus,” the country’s health ministry in a statement.

The Scientist

Dengue and chikungunya

Will environmentalists relent and allow DDT in the U.S. again now that both Aedes aegypti and Anopheles quadrimaculatus mosquitoes have returned in force? Dengue fever, called break bone fever, and chikungunya, pronounced chik-en-gun-ye whose major symptoms are fever and joint pain (name means “that which bends up”) have been appearing in the U.S. due to travel and mosquitoes spread the virus.

Of course, the ban on DDT killed millions in Africa and Asia.  Will they relent for Americans?

http://www.examiner.com/article/dengue-fever-and-chikungunya-the-coming-threat

http://www.wired.com/2014/06/us-travelers-chikungunya/

Mosquito Borne Diseases: What Diseases Do They Carry? (pest-help.com)

http://www.scientificamerican.com/article/debilitating-virus-infect/

Given a choice between dengue fever or another mosquito-borne disease called chikungunya fever, choose dengue every time. Neither has an available vaccine or treatment, but chikungunya (pronounced chik-un-GUHN-ya) is far more severe – it literally means “that which bends up” because patients are often stooped over from debilitating joint pain.

http://www.biomedcentral.com/1471-2164/15/174

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Guess who's coming to dinner?

During the last two decades, Dengue Fever has been on the increase in Latin America and the Caribbean. It’s a mosquito transmitted disease with 4 virus serotypes, and having one doesn’t make a person immune-- he can get the other three. Each infection places the person at greater risk for Dengue Hemorrhagic Fever (DHF), a life threatening condition. There is an outbreak on the Mexican side of the Mexico-Texas border. So guess who’s coming to dinner? This is reported in a recent issue of JAMA. This content is free, and well worth reading when you get tired of hearing about bird flu and MRSA on CNN or Fox.

JAMA, although one of my favorite journals, has a strong liberal editorial bias when it comes to health issues which are impacted by current public policy, so no mention is made in this issue about U.S.-Mexico border security, only that, "Clinicians in the south Texas area and members of the public should be aware of the potential for DHF in addition to dengue fever in the region." Gee, thanks for the heads up.

JAMA also doesn’t go back to basics and point out that dengue fever, because it is mosquito spread, can be controlled with DDT. Although just a few mosquitoes can infect an entire household with the virus and those people can in turn infect co-workers and schoolmates, neither JAMA nor the WHO document it cites, mentions control of mosquitoes with DDT.

However, a 2005 document at Yale Global let it slip out:

"Dubbed "breakbone fever" when it was first diagnosed more than three centuries ago, because it causes extreme pain in the joints, dengue began its global spread around Asia during World War II, when it traveled with warring armies from country to country. After the war, Aedes mosquitoes and dengue flourished along with Asia's rapid population growth and urbanization and then was carried aboard ships and planes to Africa and the Mediterranean.

When the use of the insecticide DDT in Latin America was stopped in the 1970s after the apparent eradication of yellow fever, which Aedes mosquitoes also carries, dengue was able to stage a comeback in the New World."

The virus seems to be going first class these days, using airplanes to travel, plastic lids and containers for breeding, and residing in clean, urban settings. You definitely will not need to be living in a swampy rural area to get this virus. Dengue currently infects about 50 million people, particularly in Asia, and has researchers scratching their heads, looking at computer models, and apply for grants. "Warming globalists" will note in their hot air, alarmist messages how these diseases were once defeated, but will blame global warming on their resurgence without mentioning that DDT could be among the tools to help control them.

Maybe they think mosquitoes are on the endangered species list and need to be protected?

[Emerging Infectious Diseases also notes its mysterious suppression and then reemergence, but doesn't say why or how. The decade of the 1970s seems to hold the secret. . . could it be. . .? "In the Pacific, dengue viruses were reintroduced in the early 1970s after an absence of more than 25 years. Epidemic activity caused by all four serotypes has intensified in recent years with major epidemics of DHF on several islands. Despite poor surveillance for dengue in Africa, epidemic dengue fever caused by all four serotypes has increased dramatically since 1980. . . In 2005, dengue is the most important mosquito-borne viral disease affecting humans; its global distribution is comparable to that of malaria, and an estimated 2.5 billion people live in areas at risk for epidemic transmission."