4005

Naturally aged skin

That'd be mine. Yes, I stayed out of the sun--haven't had a real sun tan since I was 19 (although skin damage starts very young), and I'm not a smoker. But I am very fair. Sun, cigarettes and pale skin are the big three for wrinkles. So can this be reversed? Yes, according to a new study in Archives of Dermatology, 2007; 143:606-612.

The study was done on 36 residents of nursing homes with an average age of 87 using topical 0.4% retinol lotion, 3 times a week for 24 weeks on the arms.

"Conclusions: Topical retinol improves fine wrinkles associated with natural aging. Significant induction of glycosaminoglycan, which is known to retain substantial water, and increased collagen production are most likely responsible for wrinkle effacement. With great skin matrix synthesis, retinol-treated aged skin is more likely to withstand skin injury and ulcer formation along with improved appearance."

Or you can put on 20 lbs. and fill out your own wrinkles (that's not in the article, but is from personal experience).

WebMD summary
ScienceDaily summary