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Ask your doctor about

low dose aspirin. Especially if you are a woman.

Story from Medscape.com, as reported in the March 26 Archives of Internal Medicine

"In this prospective, nested, case-control study, 79,439 women enrolled in the Nurses' Health Study who had no history of cardiovascular disease or cancer provided data on medication use biennially since 1980. Relative risk (RR) of death according to aspirin use was determined before diagnosis of incident cardiovascular disease or cancer and during the corresponding period for each control subject.

During 24 years, there were 9477 deaths documented from all causes. Compared with women who never used aspirin regularly, women who reported current aspirin use had a multivariate RR of death from all causes of 0.75 (95% confidence interval [CI], 0.71 - 0.81). Risk reduction was more evident for death from cardiovascular disease (RR, 0.62; 95% CI, 0.55 - 0.71) than for death from cancer (RR, 0.88; 95% CI, 0.81 - 0.96).

Aspirin use for 1 to 5 years was associated with a significant reduction in cardiovascular mortality (RR, 0.75; 95% CI, 0.61 - 0.92), whereas a significant reduction in risk for cancer deaths was not observed until after 10 years of aspirin use (P for linear trend = .005). The benefit associated with aspirin was confined to low and moderate doses, and it was greater in older women (P for interaction < .001) and in women with more cardiac risk factors (P for interaction = .02).

"In women, low to moderate doses of aspirin are associated with significantly lower risk of all-cause mortality, particularly in older women and those with cardiac risk factors," the authors write. "A significant benefit is evident within 5 years for cardiovascular disease, whereas a modest benefit for cancer is not apparent until after 10 years of use." "

I have a very conservative doctor, and have been on low dose aspirin probably 7 or 8 years.