Amiodarone and the elderly, >75

Summary from 2019: Aust Prescr 2019 Oct 1;42(5):158–162. Amiodarone in the aged - PMC

Amiodarone in the aged

"Amiodarone is widely considered to be the most effective antiarrhythmic drug available.1 It is commonly used to treat atrial fibrillation and ventricular arrhythmias. Amiodarone, and its active metabolite desethylamiodarone, have multiple effects on cardiac depolarisation and repolarisation. Although it primarily blocks potassium channels, amiodarone potentiates its effect through all four of the classic Vaughan Williams mechanisms of antiarrhythmic action.

Despite its efficacy, amiodarone is a challenging drug to use in clinical practice due to its prolonged half-life, multiple adverse effects and drug interactions. These adverse effects are particularly problematic for older people who are more susceptible to drug toxicities and who have higher rates of polypharmacy. There is also a lack of information regarding the safety of amiodarone in older people.2 A cardiologist’s opinion is recommended before prescribing. 

[Unfortunately, it was prescribed by a cardiologist.]

Amiodarone can have adverse effects in multiple organ systems including the lungs, heart, liver, thyroid, gut, skin, nerves and eyes.3 Its use is also implicated in a range of drug–drug interactions with commonly prescribed cardiovascular drugs.4"

Also read from 2025: The Safety Profile of Amiodarone Among Older Adults (Age ≥75 Years): A Pharmacovigilance Study from the FDA Data. | Read by QxMD

CONCLUSIONS: In this global postmarketing study, interstitial lung disease and bradycardia were more frequently reported in older adults treated with amiodarone. These findings support vigilant monitoring for these adverse events, particularly in older patients.

In our case, there was "no vigilant monitoring."

Hot Showers and Syncope (fainting)--Risks and Triggers

How It Happens

• Vasodilation: Hot water causes blood vessels in your skin and extremities to widen.

• Blood Pooling: Standing up adds gravity, pulling blood into your lower legs. Combined with heat-induced vasodilation, more blood pools away from your core.

• Drop in Blood Pressure: Less blood returns to your heart and brain, causing a temporary drop in blood pressure and reduced cerebral blood flow, which triggers a faint.

Common Triggers & Risk Factors

• Dehydration: Low fluid volume makes blood pressure drops much more likely.

• Prolonged Standing: Locking your knees or standing still in a hot stall increases lower-limb blood pooling.

• Underlying Conditions: Arrhythmias, low blood pressure (hypotension), or certain medications (like diuretics or sedatives) raise your risk.

• Exertion or Post-Workout: Showering immediately after a heavy workout keeps blood vessels dilated longer.

• Underlying Conditions: Arrhythmias, low blood pressure (hypotension), or certain medications (like diuretics or sedatives) raise your risk.

• The Exertion or Post-Workout: Showering immediately after a workout keeps blood vessels dilated longer.

Prevention and Safety Tips

• Lower the Temperature: Use warm or lukewarm water instead of very hot water.

• Stay Hydrated: Drink a glass of water or an electrolyte drink before stepping in.

• Sit Down: Use a shower stool or chair if you are prone to dizziness.

• Keep Moving: Gently shift your weight and avoid locking your knees while standing.

• Cool Down: Finish your shower with a splash of cooler water.

Who is responsible, Biden or the church organizations?

Between January 1 and December 31, 2023, more than 520,000 people crossed the Darién Gap, nearly double the 248,000 who crossed in 2022 and more than triple the 133,000 who crossed in 2021. These were Biden's invaders, invited with promises of money and safety in sanctuary cities despite our laws. It's a horrible trek especially for women and children.

 
But they couldn't have made their way through that treacherous terrain without the help of Christian organizations many paid by our Protestant and Catholic bureaucracies. The organizations that helped them with food and shelter and even rape kits. 

Among Lutherans alone under the Biden administration, Lutheran Immigration and Refugee Service (now renamed Global Refuge) received over $881 million in U.S. government grants for migrant and refugee assistance, with annual amounts in FY 2021 and FY 2022 exceeding $93 million and $182 million respectively. Obviously not all that was spent in Panama or at our border, but that's a lot of salaries and support services and also the creation of small communities that never existed before. When bus loads disgorged in NYC or Washington DC you may have noticed from media coverage or TikTok reels how well dressed the invaders were--good shoes, clothing appropriate for the season, cell phones, etc. Your own congregations may not be as well fed and shod.

Shocking to me, and I asked Chat-gpt several ways, there is no record of or even if the individual congregations of Lutheran or Catholic of Baptists ever gave any money for these "good works."

https://www.doctorswithoutborders.org/latest/darien-gap-we-crossed-jungle-looking-better-future-not-our-lives-end

Bernie Sanders

If you ever thought one man or one vote couldn't make a difference, just think of Bernie Sanders. At one time he was the only "Democratic Socialist" in the Democrat Party--in fact, he didn't even call himself a Democrat, just said he was an Independent who ran for office of President as a Democrat. They really walked all over him and didn't accept him then--chose Obama and Hillary--but look at him now! He refers to the Democrat Party as "my party." It's now loaded with Communists and Islamo-Fascists. Biden led an army of 11 million invaders, and Hillary began stealing health care in Bill's first term, allowing AOC and Bernie to take up the call. While Bernie criticizes billionaires who have actually built something and provided jobs for you the people, he is a millionaire and laughs in your faces as you are blinded by an "affordability" crisis, the price of gasoline, so you ask/vote for more of what brought down Venezuela and Cuba. Yes, one man can make a difference,, and it will take a lot of votes to stop his global reach.

PolitiFact | What Bernie Sanders has said about the Democrats over the years

Transgressive poetry

Today I found a poetry term I didn't understand: "Transgressive poetry: Poetry that deliberately violates social, moral, or aesthetic norms; challenges taboos around language, body, or politics; associated with confessional and avant-garde movements." I suspect it must have been 20th century poets.

I tried to imagine what that would be in the 21st century when half the populace believes it's OK to kill preborn humans so the world could have more bats or jungles (but not more cows or cats); and calling a movie star fat when she is and moves to Ireland is equivalent to rape, but calling the President a Nazi or Fascist is just normal speech; or cutting off the breasts of young girls and loading them up with testosterone is compassionate care, but teaching them about Jesus would be violating her freedom and personhood.

The riots in France--not a student protest

My computer screen opened with the amazing Millau Viaduct in southern France built to relieve the tourist traffic in that scenic area and only recently surpassed by China as an engineering wonder. I wondered how it had survived the unrest. No mention. But that put me into the news at "France24." French media are just as naive and dumb as ours--still say it's a student protest. Dumb as U.S. Democrats.

Covid and the Amish--a flawed study exposed

If you ever wish to poke holes in the "peer reviewed" myth of authenticity and excellence in medical studies, you could use the fact of mixing Mennonites in with the Amish in this so-called research on the Amish and Covid. But there are so many other flaws in this (and others in this report) you really should reconsider getting that shot. Protect the researcher, protect the grant money, but most of all protect the producer of the product.

https://brownstone.org/articles/how-a-flawed-covid-study-tried-and-failed-to-discredit-the-amish/

Welcome to Columbus, Ghanan nurses

Columbus , Ohio, Mayor Andrew J. Ginther has signed a formal agreement with Ghana to create legal, structured pathways for Ghanaian-trained nurses to work in Ohio’s healthcare system
(theheraldghana.com), BTW we have 4 major health systems here--Trinity, OSU, Nationwide Childrens and OhioHealth with 4 or 5 smaller ones.

 If the mayor did it, then it's tax payer dollars. I looked up the price tag for nurses in general for Columbus metro area and it's already $20,000 below the national median whether entry or higher level. Columbus is Democrat run and locked down, top to bottom, and claiming that they will give mid-Ohio a better deal if we just vote Democrat. Counting Ohio State we already have 9 nursing schools here, and supposedly these immigrants are already trained and ready to go. I'm sure they have family for chain migration (U.S. federal law). If housing is tight for low income and non-whites, how does importing Ghanans help the economy and Columbus people hoping to move up through more education and good job opportunities? Can they really do a better, safer job than our home grown whom we've already paid to educate and acculturate?

The Presidents and Iran

 

Who is Susan Kokinda?

Times of Israel, blogs by Avi Schwartz

"Susan Kokinda is not a typical media pundit. She represents a school of political and economic thought that sees today’s events not as isolated headlines, but as part of a long historical struggle over sovereignty, industry, finance, empire, and national destiny.

Promethean Action describes itself as a movement dedicated to “defying oligarchy” and unleashing human creativity. Promethean Action has spent decades arguing for the revival of the American System: industry, infrastructure, productive labor, scientific progress, tariffs, national banking, and the rebuilding of the real economy."

Maybe the American Revolution isn't over?

The Blogs: Susan Kokinda, the American System, and the Battle Behind the Headline | Avi Schwartz | The Times of Israel

Judith Core Gowdy (Judy) — 1940–2024

When Judy and John and their sweet daughters lived in Upper Arlington, Ohio, they attended Upper Arlington Lutheran Church which is where we met.  We had both attended a Cursillo Week-end and we became members of a small group.  Our church benefitted from her artistic talent. This obituary was in the Seattle Times in 2024.

"Judith Core Gowdy, née Judith Ellen Core, was born May 28, 1940, in southern California to Ed and Margaret Core, and later moved with her family to Portland, Oregon, where she graduated from Lincoln High School. She attended the University of Oregon, joined the Sigma Kappa Sorority, and earned a degree in Interior Architecture.

In 1962, Judy moved to Seattle, starting her career at design firm William L. Davis. She married John in 1967, and together they raised two daughters, Minda (1972) and Carlin (1975). The family lived in Seattle, Upper Arlington, OH, Westfield, NJ, and Bellevue, WA, with a life filled with family traditions, volunteer work, and creative projects.

Her career reached its peak in Bellevue, where she founded her own interior design business, served as President of the local ASID chapter, and later received its lifetime achievement award. She was also active in the Women’s University Club of Seattle. Judy was known for her warmth, creativity, and dedication to family and community, and she passed away on June 12, 2024.

 https://obituaries.seattletimes.com/obituary/judith-gowdy-1090163782?