“In the study, which was funded by the National Institutes of Health, there were no significant differences between patients who received injections of triamcinolone hexacetonide every 12 weeks and those given placebo in change in pain on the Western Ontario and McMaster University Arthritis Index (WOMAC), with differences of -2.2 in the steroid group and -2.8 in the placebo group (P=0.3), reported Timothy E. McAlindon, MD, of Tufts University in Boston.”
"I think we can conclude that intra-articular corticosteroids used at the dose of 40 mg for 2 years has no major effect on structure in the joint -- either deleterious or beneficial -- and that over the long-term we don't see an overall effect on patient-reported outcomes or physical function," he said [Timothy McAlindon].
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