Amiodarone side effects

My husband was diagnosed in January with acute heart failure and was first assigned to an a-fib clinic, and then heart management then to surgery for a pacemaker with defibrillator. Along with a clutch of other drugs including Lasix he was prescribed Amiodarone on January 24.  After that he just got sicker and sicker to the point he can do little other than sleep in a chair and open an eye to watch football. If we have 2 good days in a row, we call it good, but today his vomiting was as bad as I can remember, but mostly dry heaves since he hadn't eaten yet. 

So, let's look at Amiodarone side effects, which seems to be the primary culprit and is for abnormal heart rhythms. He was removed from it about 2 weeks ago. Because he was on it for months, who knows if we can get out of his system. BTW, no one has suggested staying out of the sun or that he might have skin or eye problems from this.

This is AI generated from about 3 sources--something any of the many doctors, RNs or Nurse Practitioners could have looked up or used talk to text. Words like "monitoring" or "immediate attention" are a joke. We could walk to the clinic faster than getting a call back. . .except he can't walk.

"Amiodarone is a potent antiarrhythmic medication known for causing a wide range of side effects that affect multiple organ systems, ranging from common, mild issues to rare, life-threatening toxicities.

Common Side Effects
Most patients experience mild gastrointestinal and neurological symptoms, including nausea, vomiting, constipation, loss of appetite, dizziness, tremors, and fatigue. Dermatological effects are also frequent, specifically photosensitivity (sun sensitivity) and a reversible blue-gray discoloration of exposed skin. Corneal microdeposits occur in nearly all long-term users, often causing blurred vision or halos around lights, though permanent vision loss is rare.

Serious Adverse Reactions
The most critical risks involve pulmonary toxicity (lung inflammation or fibrosis), hepatotoxicity (liver damage), and thyroid dysfunction (both hypothyroidism and hyperthyroidism). Cardiac complications may include bradycardia (slow heart rate), heart block, and QT prolongation, which can paradoxically worsen arrhythmias. Other severe reactions include optic neuropathy (potential blindness), peripheral neuropathy, and severe allergic reactions such as Stevens-Johnson syndrome.

Precautions
Patients must avoid grapefruit and sun exposure while taking this medication. Regular monitoring of lung function, liver enzymes, thyroid levels, and eye exams is required to detect toxicity early. Symptoms such as persistent cough, shortness of breath, yellowing of the skin, or unexplained swelling require immediate medical attention.

Syncope in older adults

 Syncope in Older Adults - What You Need to Know

Or why are you fainting?

What is syncope?

Syncope is also called fainting or passing out. Syncope is a sudden, temporary loss of consciousness, followed by a fall from a standing or sitting position. A syncope episode is usually short.

What causes or increases my risk for syncope?

Syncope is caused by a decrease in blood flow to the brain. When blood flow to the brain decreases, oxygen to the brain also decreases. Any of the following conditions may cause syncope:

Medicines such as blood pressure medicine or antidepressants, or use of multiple medicines

A medical condition such as severe anemia, a nerve disorder, asthma, or hyperventilation (breathing too quickly)

A heart condition, such as a narrow artery or an irregular heartbeat

Dehydration

Problems with the blood vessels of your brain

Bleeding, especially in your stomach or intestines, or a blood clot that passes through your lungs

A rapid drop in blood pressure after a body position change, such as moving from lying to sitting or standing

Straining during bowel movements, a cough or sneeze, or a stressful or fearful situation

What signs and symptoms may occur before syncope?

Cold, clammy, and sweaty skin

Fast breathing and a racing, pounding heartbeat

Feeling more tired than usual

Nausea, a warm feeling, sweating, and lightheadedness

A headache or dizziness

Tingling sensation or numbness

Spots in front of your eyes, blurred vision, or double vision

How is the cause of syncope diagnosed?

Your healthcare provider will examine you and ask about your symptoms. Tell your provider everything you know about your syncope episode. Include where you were when you fainted and what you were doing before symptoms started. Your provider will ask about your medical history, including any heart conditions in your family. Ask anyone who saw you faint to come with you to tell the provider details of what happened. Your provider may order the following tests to find out what is causing your symptoms:

Blood tests may be done to find the cause of your syncope.

Telemetry is continuous monitoring of your heart rhythm. Sticky pads placed on your skin connect to an EKG machine that records your heart rhythm.

An echocardiogram is a type of ultrasound. Sound waves are used to show the structure and function of your heart.

A stress test may show the changes that take place in your heart while it is under stress. Stress may be placed on your heart with exercise or medicine. Ask for more information about this test.

A Holter monitor is also called a portable electrocardiography (EKG) monitor. It shows your heart's electrical activity while you do your usual activities. The monitor is a small battery-operated device that you wear. It will show how fast your heart beats and if it beats in a regular pattern. Your provider may recommend this if you have syncope often over 2 to 3 days.

How is syncope treated?

Treatment depends on the cause of your syncope. To prevent syncope from happening again, you may need any of the following:

Medicines may be needed to help your heart pump strongly and regularly. Your healthcare provider may also make changes to any medicines that are causing syncope.

Tilt training involves training yourself to stand for 10 to 30 minutes each day against a wall. This helps your body decrease the effects of posture changes and reduces the number of fainting spells.

What can I do to manage syncope?

Keep a record of your syncope episodes. Include your symptoms and your activity before and after the episode. The record can help your healthcare provider find the cause of your syncope and help you manage episodes.

Sit or lie down when needed. This includes when you feel dizzy, your throat is getting tight, and your vision changes. Raise your legs above the level of your heart. Your provider may also recommend that you keep the head of your bed elevated. This can help keep your blood pressure from dropping too low.

Check your blood pressure often. This is important if you take medicine to lower your blood pressure. Check your blood pressure when you are lying down and when you are standing. Ask how often to check during the day. Keep a record of your blood pressure numbers. Your provider may use the record to help plan your treatment.

Use assistive devices as directed. Your provider may suggest that you use a cane or walker to help you keep your balance. You may need to have grab bars put in your bathroom near the toilet or in the shower.

What can I do to prevent a syncope episode?

Know and avoid your triggers. Certain events may bring on syncope. These events may cause you to feel under pressure, upset, or fearful. When you feel the symptoms, you can make movements to prevent a syncope episode. For example, make a fist, cross your legs, squeeze your thighs together, or tighten your arm muscles.

Move slowly and let yourself get used to one position before you move to another position. This is very important when you change from a lying or sitting position to a standing position. Take some deep breaths before you stand up from a lying position. Stand up slowly. Sudden movements may cause a fainting spell. Sit on the side of the bed or couch for a few minutes before you stand up. If you are on bedrest, try to be upright for about 2 hours each day, or as directed. Do not lock your legs if you are standing for a long period of time. Move your legs and bend your knees to keep blood flowing.

Follow your healthcare provider's recommendations. 

Your provider may recommend that you drink more liquids to prevent dehydration. You may also need to have more salt to keep your blood pressure from dropping too low and causing syncope. Your provider will tell you how much liquid and sodium to have each day. Your provider will also tell you how much physical activity is safe for you. This will depend on what is causing your syncope.

Watch for signs of low blood sugar. These include hunger, nervousness, sweating, and fast or fluttery heartbeats. Talk with your provider about ways to keep your blood sugar level steady.

Do not strain if you are constipated. You may faint if you strain to have a bowel movement. Walking is the best way to get your bowels moving. Eat foods high in fiber to make it easier to have a bowel movement. Good examples are high-fiber cereals, beans, vegetables, and whole-grain breads. Prune juice may help make bowel movements softer.

Be careful in hot weather. Heat can cause a syncope episode. Limit activity done outside on hot days. Physical activity in hot weather can lead to dehydration. This can cause an episode.

https://ubiehealth.com/doctors-note/vasovagal-syncope-age65-causes-prevent-fainting-37123exp4

Cardioversion

 Today my husband went to Riverside (Ohio Health) for a cardioversion. Although he had 4 stints in 2020 and 2021, in recent months he had developed atrial fibrillation. My personal, non-medical opinion is it was due to the stress of moving.

"Cardioversion is a medical treatment that uses quick, low-energy shocks to restore a regular heart rhythm. It's used to treat some types of irregular heartbeats, called arrhythmias. An example is atrial fibrillation (AFib). Sometimes cardioversion is done using medicines." Mayo Clinic

I spoke with the doctor after the successful procedure about the causes and future care.  Got a little of this and a little of that. Mostly things we can't change like genes and age.

Cardioversion: Procedure, side effects, and recovery 

The hospital is constantly under construction. When we got there today the Red parking garage/drop off had a detour, so we had to return to the main road and go around the building to get to the drop off. In 1980 a book was published titled, "The Hospital that Ate Chicago." I think there's one in Columbus.