Sunday, October 15, 2017

Columbus Marathon today

The marathon benefits Children’s Hospital. Everyone is psyched.  Well, not me.  I’m just watching the weather.  Nearly 70 degrees at 5:30 a.m., but windy, and will cool down this afternoon.  I just want to be able to get out and walk.

 It’s good for the brain.

This link only provides the summary, but has an excellent graphic to remind you what lifestyle changes can help your brain.  You want to stay of the right (green) side, and avoid the lavender/purple.

“Diet, stress, and physical exercise directly act on neural stem cells and/or their progeny, but, in addition, they may also indirectly affect neurogenesis by acting on microglia. Microglia, the guardians of the brain, rapidly sense changes in the brain milieu, and it has been recently shown that their function is affected by lifestyle factors. However, few studies have analyzed the modulatory effect of microglia on adult neurogenesis in these conditions. Here, we review the current knowledge about the dialogue maintained between microglia and the hippocampal neurogenic cascade. Understanding how the communication between microglia and hippocampal neurogenesis is affected by lifestyle choices is crucial to maintain the brain cognitive reserve and prevent the maladaptive responses that emerge during disease or injury through adulthood and aging.”


“Cardiovascular exercise such as running, interval training, cross fit and or yoga are the single most effective ways of boosting neurogenesis; they come with a vast array of health benefits for mind and body, and are also important stress relievers. The endorphins produced acting as a potent antidote to cortisol, the stress hormone. Exercise has been found to increase levels of brain derived neurotrophic factor (BDNF) and glial cell line-derived trophic factor (GDNF), two key growth factors supporting neurogenesis.  It also increases hormones such as testosterone which also seem to have a extremely beneficial effect on neurogenesis, and act as a buffer against the effects of psychological stress. This is increasingly more important as we age.”  Of course, I don't run, but a brisk walk is good, too.

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