Sunday, November 07, 2021

Dr. Syed Haider on Off label use of drugs

Dr. Syed Haider has his own website where you can ask questions. Definitely don't take FB warnings at face value. Big Tech, Big Pharma, and Big Government seem to be glued together in a very sticky snowball rolling down hill.

From his website discussing "off label" use.

"Many in the media and medical establishment have played up the fact that ivermectin (and earlier hydroxychloroquine) are unproven, off-label and therefore dangerous therapies.

So what is off-label use anyway?

It just means that the FDA has approved a medication for one use and it is being used for another.
Off-label prescribing is very common, reason being it costs a lot to fund clinical trials to “prove” a drug is effective for an indication, but if a drug is reasonably safe and there is good reason to believe it might work for a problem (e.g. test tube studies or just general physiological plausibility) physicians try it out on patients, especially when no other medications work.

Common examples of off-label use include all the following:

Aspirin for primary prevention of cardiovascular disease, carotid artery atherosclerosis, carotid artery stenting, primary prevention of colorectal cancer; acute migraine, PCI for stable ischemic heart disease, pericarditis, peripheral vascular disease, polycythemia vera, prevention of preeclampsia, prevention of thrombosis in: surgical prosthetic heart valve replacement, transcatheter aortic valve replacement and transcatheter mitral valve repair with MitraClip device; and the prevention of DVT after total hip or knee arthroplasty.

Ivermectin itself for ascariasis, demodicosis, gnathostomiasis, hookworm-related cutaneous larva migrans, lice, mansonella ozzardi infection, mansonella streptocerca infection, scabies, trichuriasis, and wucheria bancrofti infection (try telling someone with lice or scabies they can’t use a curative course of IVM because it’s off-label and thus unproven and too dangerous).

Ibuprofen for gout and pericarditis (if you’ve had gout you don’t need the FDA telling you high dose ibuprofen works – it’s rather obvious).
Wellbutrin/Bupropion for smoking cessation.
Neurontin/Gabapentin for bipolar, essential tremor, hot flashes, migraine prevention, neuropathic pain, phantom limb syndrome, and restless leg syndrome.
Magnesium sulfate for premature labor and preeclampsia.
Seroquel for insomnia.
Zoloft for premature ejaculation.
None of these would be used if, above all, practical experience, and after that many small, underpowered and somewhat flawed studies, did not show they worked.

(And from me for a public service) Modafinil for people with no thyroid so they can stay awake.

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