Researchers at Indiana University have combined scaling laws with a model of biodiversity to produce a new estimate of the number of microbial species on Earth: somewhere between 100 billion and 1 trillion. (The Scientist, May 4). And at the other end, Hubble reveals an estimated 100 billion galaxies in the universe or so, but this number is likely to increase to about 200 billion as telescope technology in space improves. Minor league stuff--the human body may have 37.2 trillion cells--depends on who is counting--and each cell has a sex--male or female. But hey, it's all an accident, it all evolved. No thought or design.